25-100700 YE-12010mg 383124-82-1

英文名 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile; [3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile; CAS号 383124-82-1
产品编号 25-100700 分子式 C16H9Cl2N3O
产品分类 专用科研试剂 分子量 330.17
产品性质 储存条件
COA MSDS 货期咨询
货号:25-100700
中文名称:YE-120
英文名称:Yohimbine Hydrochloride
CAS号:383124-82-1
重量:10mg
重量:100mg
分子式:C16H9Cl2N3O
别名:2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile; [3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile;
应用介绍:YE-120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). YE-120 also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM). GPR35 is a Class A, rhodopsin-like G protein-coupled receptor which is predominantly expressed in immune and gastrointestinal tissue, with notable expression in the ileum (rat and human GPR35), the spleen (rat and murine GPR35) and the pancreas (human GPR35).
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